ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2016, Vol. 47 ›› Issue (6): 1260-1265.doi: 10.11843/j.issn.0366-6964.2016.06.023

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Distribution of Oxytocin Receptor in the Carotid Body of Female Goat

HUANG Shuang,SUN Man,JIN Xiu-fang,XU Yong-ping*,LI Qiang   

  1. (College of Animal Medicine,Northwest A&F University,Yangling 712100,China)
  • Received:2015-12-15 Online:2016-06-23 Published:2016-06-23

Abstract:

This experiment was conducted to detect the existence of oxytocin receptors (OTR) in the carotid body (CB) of female goats to discuss effects of oxytocin (OT) on the activity of CB.The distribution characteristics of OTR in the carotid body of female goats were studied by using immunohistochemical SP staining.The results showed that,the parenchyma cells and the interstitial tissue were immunolabelled in different degrees.In the type Ⅰ cells and type Ⅱ cells of CB,uniformly strong immunostaining was found in the whole cell membrane and cytoplasm,whereas the nucleus of type Ⅰ cells were not or weekly immunolabelled,the nucleus of type Ⅱ cells were strong immunolabelled.In the interstitial tissue,moderate immunoreactivity products distribute in the vascular endothelial cells and nerve fibers.Image analysis documented a significant difference of OTR expression between the parenchyma cells and the interstitial tissue.The OTRs were widely distributed in CB of female goat,suggesting that oxytocin may exert potential effects on carotid body.

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